Nitric Oxide: The Molecule Of Life

Didem Miraloglu, MD, MS

Nitric oxide (NO) is a remarkable molecule that plays a crucial role in various physiological processes within the human body. Discovered in the late 18th century, and its importance has been extensively studied and recognized in the fields of medicine, biology, and biochemistry. In fact in 1998 Nobel Prize in Physiology or Medicine was awarded to Robert Furchgott, LouisIgnarro, and Ferid Murad, for their discoveries of NO as a signal molecule in the vasculature and specifically in the control of blood pressure. NO is a unique signaling molecule that influences numerous cellular pathways, contributing to cardiovascular health, immune function, neurotransmission, and even cellular defense against pathogens.
The synthesis of nitric oxide is achieved through the enzymatic action of nitric oxide synthase (NOS) on L-arginine, a semi-essential amino acid found in the body. There are three isoforms of NOS: endothelial NOS(eNOS), neuronal NOS (nNOS), and inducible NOS (iNOS). Each isoform is expressed in specific tissues and cells and responds to different stimuli. eNOSis predominantly present in endothelial cells, contributing to vasodilation and regulating blood flow. nNOS is found in neurons and plays a role in neuro transmission, while iNOS is induced in response to inflammation or immune challenges.

The regulation of nitric oxide production is a tightly controlled process. Various factors, including calcium ions, cofactors like tetrahydrobiopterin, and the availability of L-arginine, affect NOS activity. This precise control ensures that NO is produced when needed, preventing excessive generation and potential cellular damage.

Nitric oxide is a key player in cardiovascular health. It acts as a vasodilator, relaxing the smooth muscles in blood vessel walls, which leads to increased blood flow and improved oxygen and nutrient delivery to tissues. Dysfunction in the NO pathway is associated with numerous cardiovascular diseases, including hypertension, atherosclerosis, and heart failure. Pharmaceutical agents that enhance NO production or mimic its actions, such as nitroglycerin and sildenafil (Viagra), have become essential treatments for these conditions.

The immune system relies on nitric oxide to fight off pathogens and defend against infections. When activated by cytokines and other immune molecules, iNOS produces NO in macrophages and other immune cells. Nitric oxide acts as a potent antimicrobial agent by damaging bacterial DNA, proteins, and lipids. Furthermore, it helps regulate the immune response and plays a role in resolving inflammation after an infection has been controlled.
In the nervous system, nitric oxide is a critical neurotransmitter involved in various processes, such as learning and memory, synaptic plasticity, and neuronal communication. It modulates the release of neurotransmitters like dopamine, serotonin, and glutamate, contributing to mood regulation and cognition.

Moreover, NO has been linked to neuroprotection by its ability to act as an antioxidant and counteract oxidative stress-induced damage. Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, involve oxidative stress, and researchers are exploring the potential of NO-based therapies to mitigate neuronal damage.

Due to its diverse roles in numerous physiological processes, nitric oxide has garnered significant interest as a potential therapeutic agent. Researchers are exploring its use in various medical applications, including wound healing, erectile dysfunction, and respiratory disorders like pulmonary hypertension. Additionally, NO-based therapies are being investigated in the context of cancer treatment, where NO has shown potential to inhibit tumor growth and sensitize cancer cells to radiation and chemotherapy.

Nitric oxide, once regarded merely as an air pollutant, has emerged as a fundamental molecule essential for life and well-being. Its roles in cardiovascular health, immune function, neurotransmission, and neuroprotection highlight its significance in maintaining the body’s delicate balance.

As our understanding of this remarkable molecule deepens, we are likely to witness further advancements in medical therapies that harness the potential of nitric oxide for improving human health and well-being.

To schedule a new patient appointment, please call our office at 919-999-0831.

Your Partner In Health,
Didem Miraloglu, MD, MS

Low SIgA- Part 1

Shane Hemphill, MD

Say your functional medicine provider ordered a stool test and it showed Low SIgA- what does that mean and how did it develop?

The immune system makes T cells and B cells. The B cells produce secretory IgA (SIgA) which acts as a first line of defense against the entry of foreign substances into the body.  These foreign substances include many things such as undigested proteins from the foods that we eat, bacteria, viruses, parasites, or even molds.  In essence SIgA gives us insight into what is happening at our mucosal surfaces.

The body’s mucosal surfaces – located at the eyes, ears, nose, throat, sinuses, gastrointestinal and genitourinary tracts, and skin are all entry points for potential disease-causing pathogens.

Our body’s way of protecting these entry points is done with the release of SIgA.  B-cells present within the mucosa are activated upon exposure to pathogens and allergens and thus produce SIgA in response.  The SIgA then attaches itself to the invading bacteria, virus or other foreign substance, traps it in the mucosal surface and then neutralizes it.

So what does it mean if your SIgA is low?
If your SIgA is low, this means that you are less able to prevent invaders from getting into your gut mucosal lining. This lining can become inflamed and tight junctions that ordinarily keep toxins and undigested food particles out – break down. This causes havoc as now toxins and undigested substances are able to get access to our blood stream, causing inflammatory and immune reactions that lead to systemic symptoms throughout the body.
Patients with low SIgA levels  generally have increased risk of food sensitivities, irritable bowel syndrome (IBS),  inflammatory bowel disease (IBD), intestinal permeability also known as ‘leaky gut’,  autoimmunity,  and other gastrointestinal infections.

What causes low SIgA levels?
Chronic infections are commonly associated with low SIgA.  Assessing for problematic bugs including H pylori, Candida, Blastocystis Hominis, H. Pylori, Clostridium difficile are essential in this evaluation. Do keep in mind that many of these normally can exist in the bowel at low levels and not cause harm. Some of them only become problematic depending on their level in the body and others do it based on virulence. These can be assessed via a functional stool test. One interesting note is that these ‘infections’ are opportunistic by nature, meaning they also come about when SIgA levels reduce. Therefore it is not uncommon to see development of Candida in SIgA compromised clients.

Medications are another cause of low SIgA. Anti-inflammatories, antibiotics and antidepressants are some examples. Studies have even shown an association between low SIgA and people that suffer from depression.

Stress is another cause of low SIgA through increased cortisol levels. Stress can be in any form, including mental, emotional or even physical. One study has even demonstrated that persistent negative thoughts about ourselves can lower our own SIgA levels. Lowering stress and introducing stress reduction techniques is vital in maintaining this protector.

Finally, poor dietary choices are another contributor to low SIgA. Certain nutrients such as Vitamin D, Vitamin A, Zinc and Glutathione are instrumental in supporting healthy SIgA levels.  A good intake of dietary fiber and phytonutrients can also play a role in supporting a healthy gut microbiome. This can lead to the development of beneficial bacteria that promote healthy levels as well.

Stay tuned for my next article which will discuss how we treat low SIgA.

To schedule a new patient appointment, please call our office at 919-999-0831. 

Your Partner in Health!
Shane Hemphill, MD

Camu Camu the Superfood

Clarissa A. Kussin, ND, FMCHC, ERYT-500

Lets dive into the powerful benefits of a superfood called Camu Camu. Known for its exceptional nutritional profile, Camu Camu offers a wide range of health benefits. Additionally, we’ve included a delightful smoothie recipe to help you incorporate this fantastic fruit into your daily routine.

Understanding Camu Camu
Camu Camu (Myrciaria dubia) is a small berry native to the Amazon rainforest in Peru and Brazil. It has gained popularity worldwide due to its extraordinarily high vitamin C content, containing up to 60 times more vitamin C per serving than an orange. However, Camu Camu offers more than just vitamin C. It also contains antioxidants, vitamins, minerals, and phytochemicals that support overall well-being.

The Health Benefits of Camu Camu

Immune Support: Camu Camu’s exceptional vitamin C content plays a crucial role in supporting a healthy immune system. Vitamin C is known for its antioxidant properties, which help protect the body against oxidative stress and strengthen immune defenses.

Antioxidant Powerhouse: In addition to vitamin C, Camu Camu contains a range of antioxidants, such as flavonoids and ellagic acid. These compounds combat free radicals, reducing the risk of chronic diseases and promoting overall health.

Collagen Formation: Vitamin C is essential for collagen synthesis, which supports healthy skin, joints, and connective tissues. Regular consumption of Camu Camu can contribute to the maintenance of youthful skin and overall joint health.

Mood Enhancement: Some studies suggest that Camu Camu may have mood-enhancing properties due to its high levels of antioxidants and other beneficial compounds. Including Camu Camu in your diet may help support mental well-being.

Anti-Inflammatory Effects: Camu Camu contains natural anti-inflammatory compounds, including anthocyanins and catechins. These compounds may help reduce inflammation in the body, supporting overall health and reducing the risk of chronic diseases.

Here’s a refreshing smoothie recipe that combines the goodness of Camu Camu with other nutritious ingredients:
Camu Berry Blast Smoothie: 2 servingsIngredients:1 cup frozen mixed berries (strawberries, blueberries, raspberries)1 small frozen banana1 /2 teaspoon Camu Camu powder1 cup unsweetened almond milk (or milk of your choice)1 tablespoon chia seeds1 tablespoon honey, date paste or maple syrup (optional, for added sweetness)A few ice cubes IF your berries are not frozen

Instructions: Place all the ingredients in a blender. Blend on high until smooth and creamy. Taste and adjust sweetness if desired by adding honey or maple syrup. Pour into a glass and enjoy this antioxidant-rich, vitamin C-packed smoothie.
Note: You can customize the smoothie by adding spinach, kale, or your favorite protein powder for an extra nutritional boost.

Where to Find Camu CamuCamu Camu is available in various forms, including powder, capsules, and freeze-dried berries. Look for organic and sustainably sourced Camu Camu products from reputable health food stores, online retailers, or local farmers’ markets.
Consider adding Camu Camu to your daily wellness routine by incorporating it into smoothies, juices, yogurt bowls, or even homemade energy bars. Experiment with different recipes to explore the unique tangy flavor and reap the numerous health benefits.

Your Partner In Health,
Clarissa A. Kussin, ND, FMCHC, ERYT-500

The Weakest Leak :

Autoimmunity and Leaky Gut Explained

They say that any system is only as strong as its weakest link. It turns out, our digestive and immune systems are only as strong as their weakest leak.

Imagine your gut as the body’s security guard. The tight junctions between the cells of your intestines decide who gets in and who doesn’t. But what happens when the gut becomes too permissive and allows unwanted guests through? That’s where “leaky gut” comes into play.

Leaky gut, or intestinal permeability, is a condition where the lining of the intestines becomes more porous than it should be. Instead of acting like a strict bouncer to the coolest club in town, the tissue starts allowing substances that shouldn’t enter your bloodstream. This includes undigested food particles, bacteria, and toxins.

When the gut barrier is compromised and unwanted intruders enter the bloodstream, your immune system, which usually only targets harmful invaders, can get confused and launch a response against your body’s own tissues instead.

It’s like friendly fire within your body! According to the NIH (National Institutes of Health) around 23.5 million (7%) Americans suffer from an autoimmune condition. And 75% of those affected are women.

Hashimoto’s thyroid disease, ulcerative colitis, rheumatoid arthritis, psoriasis, vitiligo and multiple sclerosis are some of the more than 80 known autoimmune diseases commonly seen at Carolina Total Wellness.

Three Steps to Preventing or Reversing Autoimmune Disease:
Not every autoimmune disease is curable or reversible but there are some proven steps you can take to reduce the effects on your health.

1. Manage Your Stress Stress isn’t just in your mind; it affects your gut, too. When we are facing a perceived physical or emotional threat, our bodies are wired to respond by directing resources to your vital organs and away from your digestive and reproductive functions. When you don’t have sufficient digestive enzymes and gastric acid to break foods down, they may be more irritating to your gut lining and/or penetrate the lining as larger particles than your blood stream knows how to handle. It’s not always possible to avoid stress but you can practice strategies to help you minimize the effects. Get 8 consistent hours of sleep each night. Practice saying ‘no’ – it is a full sentence. Go outside and take a walk – without devices. Laugh with a good friend.

2. Eat Gut-Healing Foods Eating a balanced diet is crucial for maintaining gut health. A diet rich in fiber, fruits, and vegetables promotes a diverse gut microbiome and a healthier gut lining. Use the rainbow as a template to guide your shopping list and eat foodsof every color several times per week. Probiotics, found in foods like yogurt, sauerkraut and kimchi help eliminate toxins and aid the digestion of nutrients from the foods you eat. Eat fermented foods several times each week to strengthen the lining of your digestive tract. Bone broth has proteins and gelatin to soothe the inner lining of the gut. Sip on some bone broth instead of coffee in the morning if you’re trying to kick the caffeine habit.

3. Fasting Fridays Once a week, skip breakfast (and the coffee/creamer.) An occasional, extended break from the hard work of digestion, also known as intermittent fasting, lets your gut clean out old debris and calms the immune system. You may discover improved mental clarity and energy, too. In fact, you may like it so much that you decide to skip breakfast two or three days a week. Healing the Gut.

If you suspect you have a leaky gut or an autoimmune disease, consult afunctional medicine practitioner. They can recommend personalized approaches like dietary changes, supplementation, and lifestyle modifications to heal your gut and reduce inflammation.

Autoimmunity and leaky gut are two puzzle pieces that fit together more than we once thought. Maintaining a healthy gut through a balanced diet, managing stress, and seeking professional guidance when needed can be your key to preventing or managing autoimmune diseases.

Remember, the journey to optimal health is unique for everyone. Keep exploring, learning, and making choices that support your well-being.  

Your Partner In Health,
Erica Nelson, MSPH, NBC-HWC

Prevention and Treatment of Viral Infections

(Including Covid, Flu, RSV and the common cold)

The providers at Carolina Total Wellness recommend the following lifestyle and supplement supports to optimize immune function, decrease viral transmission, reduce viral activity and support the body’s immune response to common viral infections.

Lifestyle:

Focus on eating foods that are organic and rich in antioxidants.  Try to eat 5 to 7 servings of vegetables and 2 to 3 servings of fruit every day.  Limit intake of sugar and processed foods.

Drink filtered water, avoiding plastics as much as possible. 

Limit intake of alcohol to no more than 2 drinks per week for women and 4 drinks per week for men.

Ensure adequate, quality sleep.  Aim for 7 to 9 hours a night, focusing on good sleep hygiene.

Integrate mindfulness and stress lowering practices every day.

Improve ventilation and air flow and utilize high quality air filters indoors, including home and work.

Nasal Spray for Prevention and Acute Exposure to Airborne Viral Illness

  1. Over the counter Covixyl is now available to help block airborne viruses from adhering to nasal membranes.  This is best used for prevention or within 4 hours of any known/expected airborne viral exposure. Follow instructions on product.
  • Xlear + Biocidin LSF (mix 5 pumps of Biocidin LSF with Xlear nasal spray) This nasal spray is an herbal anti-microbial that helps to kill viruses in the nasal mucosa.  This is best used within 1 to 2 days of any known/expected airborne viral exposure. Use 1 spray each nostril twice daily.

Prevention Supplement Options: (all supplements available in office or in online store)

  1. Orthomune – 2 caps once daily or 1 capsule twice daily (contains vitamin C 600mg, NAC 600 mg, vitamin D 2500 IU, zinc 25mg and Quercitin 250 mg)
  2. Melatonin – 3 to 6 mg daily (Long Acting Melatonin or Quick Dissolve Melatonin)

*** Orthomune and Melatonin are a great combination for viral prevention. If you prefer to take supplements individually instead of a combination product, we recommend the following;

  • Vitamin C – 500 to 1000 mg once to twice daily (Complete Vitamin C)
  • Zinc – 15 to 30 mg daily (Zinc CTW)
  • Quercitin – 200 to 400 mg daily (Allergy Ease)
  • Vitamin D3 – 2000 to 3000 IU per day (K-Force, Vitamin D3, Liquid D3)

Additional options to discuss with your provider include; curcumin (curcumin phytosome or Turmero), NAC, vitamin A, and adaptogenic mushrooms (Transfer Factor Multi Immune)

The following therapeutic options are started at the first signs of illness, positive exposure and/or positive testing.  Please notify your provider so that we can further personalize support.

Therapeutic Supplement Options: (all supplements available in or office or in online store)

  1.  Orthomune – Increase to 2 capsules twice daily (4 capsules contain vitamin C 1200mg, NAC 1200 mg, vitamin D 5000 IU, zinc 50mg and Quercitin 500 mg)
  2. Viracid – 2 capsules twice daily (contains vitamin A, C, B12, zinc, astragulus, Andrographis, echinacea, L-lysine and European elder)
  3. Curcumin – 500 to 1000 mg three times a day with food (Curcumin Phytosome)
  4. Melatonin – 3 to 6 mg at bedtime (Long Acting Melatonin or Quick Dissolve Melatonin)

***The above 4 products are a great combination for therapeutic treatment for the duration of viral illness.  If you prefer individual products, these are listed below.

  • Vitamin C – increase to 1000 mg two to three times a day (Complete Vitamin C)
  • Zinc – increase to 15 to 25 mg twice daily (Zinc CTW)
  • NAC – 500 to 1000 mg twice daily (NAC)
  • Quercitin 400 to 600 mg twice daily (Allergy Ease)
  • Vitamin D3 – 5000 IU per day (K Force, Vitamin D3, Vitamin D3 with K2, liquid vitamin D3)

Yours In Health,

Susan D. Denny, MD, MPH

How does Acupuncture work, and what can it treat?

Katie Depre LAc, LMBT, FABORM, NCCAOM

Though often described as traditional or ancient medicine, research has proven that Acupuncture has its place alongside modern medical practices. Hair-thin needles are placed in precise and therapeutic point locations along meridians. Meridians have been shown to mirror the fascial network of the body. Fascia surrounds all of the organs, muscles, bones, and nerve fibers. These points are located alongside nerve endings and blood vessels, thereby directly influencing blood flow and sensory nerves in the area (2,3). Functional brain imaging has shown changes in the brain when these points are needled (1). Since the brain controls the systems of the body (hormones, blood flow, stress responses, organ function, reproduction, etc.), influencing the brain and nervous system with Acupuncture will impact our health. Treatment encourages the body’s own systems of balance, commonly known as homeostasis.

The National Center for Complementary and Integrative Health outlines many of the researched treatable conditions (4); these include: pain management, osteoarthritis, sciatica, fibromyalgia, cancer pain, irritable bowel syndrome, asthma, depression, allergies, infertility, and menopause symptoms. Though more chronic conditions will require a series of treatment for complete resolution, I have personally witnessed immediate relief from insomnia, digestive complaints, anxiety, and pain in my clinic.  Especially because it is a non-pharmaceutical approach, many patients search out Acupuncture for treatment to acute and chronic conditions.

As a Fellow of the Acupuncture and Traditional Chinese Medicine Board of Reproductive Medicine, FABORM, I treat many patients with their fertility goals. By regulating the menses, we can prepare the body for pregnancy. Fertility work is best done weekly for three months prior to conception, as it takes three months for the egg to develop in the ovaries. During times of sympathetic stress (the flight or fight response), blood is shunted away from the ovaries and uterus. This can negatively impact egg quality and the thickness of the uterine lining.  By encouraging blood flow to these reproductive organs, switching the nervous system into a parasympathetic state (rest, digest, and repair), and regulating the Hypothalamic-Pituitary-Ovarian Axis, we set the body up for success.

For patients undergoing IVF, the Paulus Protocol is utilized. This is a series of points done before and after an embryo transfer. “Clinical pregnancies were documented in 34 of 80 patients (42.5%) in the acupuncture group, whereas the pregnancy rate was only 26.3% (21 out of 80 patients) in the control group (5).”

Please reach out today if you have specific questions on how Acupuncture can help you realize your health goals!

Warmly,

Katie Depre LAc, LMBT, FABORM, NCCAOM

Sacred-sea.com

(919) 808-2638

  1. Huang W, Pach D, Napadow V, Park K, Long X, Neumann J, Maeda Y, Nierhaus T, Liang F, Witt CM. Characterizing acupuncture stimuli using brain imaging with FMRI–a systematic review and meta-analysis of the literature. PLoS One. 2012;7(4):e32960. doi: 10.1371/journal.pone.0032960. Epub 2012 Apr 9. PMID: 22496739; PMCID: PMC3322129.
  2. Langevin HM, Yandow JA. Relationship of acupuncture points and meridians to connective tissue planes. Anat Rec. 2002 Dec 15;269(6):257-65. doi: 10.1002/ar.10185. PMID: 12467083.
  3. Bai Y, Wang J, Wu JP, Dai JX, Sha O, Tai Wai Yew D, Yuan L, Liang QN. Review of evidence suggesting that the fascia network could be the anatomical basis for acupoints and meridians in the human body. Evid Based Complement Alternat Med. 2011;2011:260510. doi: 10.1155/2011/260510. Epub 2011 Apr 26. PMID: 21584283; PMCID: PMC3092510.
  4. Acupuncture: What You Need to Know. National Center for Complementary and Integrative Health. (2022, October). https://www.nccih.nih.gov/health/acupuncture-what-you-need-to-know

What Exactly Is Applied Kinesiology?

Richard A. Laviano, DC, ND, FSBCT(c)



My doctor has recommended applied kinesiology to rebalance my vagus nerve.
Sounds like voodoo to me…. What exactly is applied kinesiology?

The importance of the vagus nerve for so many of our bodily function has been proven again and again in multiple medical studies. The vagus nerve runs from your brainstem down to your intestinal tract and is the ringmaster of your autonomic nervous system, all things “rest and digest”. When the vagus nerve is out of balance, it has the potential to create widespread dysfunction from intestinal motility (think small intestinal bacterial overgrowth) to quick “fight or flight” reactivity, anxiety, and even panic attacks.  A simple PubMed search of vagus nerve pops up34,789 results! We at CTW have come to rely on the finely tuned skills of practitioners expert in using modalities to rebalance the vagus. One of the most powerful, only in very experienced hands, is applied kinesiology (AK). Dr Rick Laviano of Falls Chiropractic and Injury in Raleigh explains below the role of AK.

Applied Kinesiology (AK) is a neurological rehabilitation therapy. At the International College of Applied Kinesiology in 2005 (1) Dr. Walter Schmitt eloquently presented a model that thoroughly explains it. He explains AK as an assessment and therapy that positively affects neurological function. We quote it here and explain it more simply below.

AK is a series of sensory receptor based diagnostic challenges followed by monitoring of manual muscle testing outcomes. All AK techniques are about creating sensory receptor stimulation that results in a net effect of excitation and inhibition leading to more optimal neurological function. These positive changes can be observed through somatic windows by changes toward normal in muscle facilitation and inhibition(muscle balance, range of motion, deep tendon reflexes) and through various autonomic windows that can also be monitored (pupil light response, blood pressure, heart rate, etc.) (pg. 1)

AK uses muscle tests as well as other neurological tests to assess the state of your nervous system. When there is poor neurological function discovered, the doctor tries his or her best to find the neurological therapy that will improve it. For example, the brainstem (area of the brain just above your neck), controls most of the things in your abdominal cavity subconsciously like your heartrate, blood pressure, gut motility, gut valves, and liver detox. We can see how healthy the brainstem is by looking at reflexes that live there, like how fast your pupils react to a shining light, or how your jaw moves, or how your balance is, or how your blood pressure compares from one side to another (2,4).

A physician trained in AK will use these nerdy tools to pinpoint what part of the nervous system may be dormant or over-excited. Then they will wake it up or calm it down through a targeted therapy such as rubbing, tapping, stretching, manipulation, eye movements, muscle/fascial work etc. AK specialists can be considered your body electricians! The ultimate goal is to improve function in the nervous system to thus improve total body health and wellness.

Since the nervous system controls every function in our bodies, there have been many types of cases Applied Kinesiologists have seen over the years. Cases that are often seen include gut/microbiome issues. It is important that these patients understand that the gut microbiome is STRONGLY influenced by the state of their gut nervous system. Improving the integrity of the nervous system in these patients can greatly improve their quality of life.

Another point worth mentioning regarding gut issues includes the trigeminal nerves. The largest cranial nerve in our brain is the trigeminal nerve. This nerve coordinates information regarding the teeth, jaw, head, and even your posture (3)!This nerve integrates (strongly connects) with the vestibular, ocular, and cerebellar reflexes that affect the health of the brainstem, even the health of the vagus nerve. By keeping the trigeminal nerve and its connections in the brainstem healthy, vagal tone is optimal! In treating gut problems, the priority is making sure that trigeminal, head, eyes, and balance organs are in tune with one another for the health of the autonomic nervous system including the vagus nerve and ultimately the gut.


References:
1.      Schmitt, Walter H., The Neurological Rationale for a Comprehensive Clinical Protocol Using Applied Kinesiology Techniques. Proceedings of the I.C.A.K. – U.S.A. Annual Meeting, Volume 1,2005-2006. p. 157-191.
2.      Monaco, A., Cattaneo, R., Mesin, L., Ciarrocchi,I., Sgolastra, F., & Pietropaoli, D. (2012). Dysregulation of the autonomous nervous system in patients with temporomandibular disorder: a pupillometric study.
3.      Cuccia, A., & Caradonna, C. (2009). The relationship between the stomatognathic system and body posture. Clinics, 64(1),61-66.
4.      Applied Kinesiology Synopsis: David S. Walther. 1988.


Your Partners In Health,
Richard A. Laviano, DC, ND, FSBCT(c) and Ana Dávila, DC Falls Chiropractic and Injury, Raleigh NC

Frances T Meredith, MD Carolina Total Wellness

Non-Toxic Cleaning Recipes


Whether you’re a new parent, someone with sensitivities to chemicals, or just looking to create a healthier home environment, the Non-Toxic Home Guide will help you tremendously.

I hope this guide is informative and helpful in your journey toward a healthier home. If you have any questions , please don’t hesitate to contact your functional medicine health coach at CTW.  We are always here to help.

RECIPES:

All-Purpose Cleaner: Mix equal parts white vinegar and water in a spray bottle. Add a few drops of your favorite essential oil for a pleasant scent.

Glass Cleaner: Mix equal parts white vinegar and water in a spray bottle. Spray the solution onto your mirrors or windows, and use a microfiber cloth to wipe them clean.

Mirror and Glass Cleaner: Mix equal parts white vinegar and water in a spray bottle. Spray the solution onto the mirror or glass surface and wipe with a clean cloth or newspaper.

Tile and Grout Cleaner: Mix 1/2 cup of baking soda with1/4 cup of hydrogen peroxide and 1 tablespoon of dish soap. Apply the solution to the tile and grout using a spray bottle or a sponge. Let it sit for 5-8 minutes before scrubbing with a soft-bristled brush. Rinse thoroughly with water.

Carpet Stain Remover: Mix 1/4 cup of white vinegar, 1 tsp of dish soap, and 1 cup of warm water in a spray bottle. Spray the mixture on the stain, let it sit for 5-10 minutes, then blot with a clean cloth.

Toilet Bowl Cleaner: Pour 2 cups of white vinegar and then 1 cup of baking soda into the toilet bowl. Let it sit for15-20 minutes before scrubbing it with a toilet brush. Flush the toilet to rinse.

Oven Cleaner: Mix 1 cup of baking soda with a small amount of water to form a paste. Apply the paste to the inside of the oven, avoiding heating elements. Let it sit for a few hours or overnight, then wipe it clean with a damp cloth.

Grease Cutter: Mix 1 cup of warm water with 1/3 cup of white vinegar, 1/8 teaspoon of dish soap, and 1 teaspoon of baking soda. Apply the solution to greasy surfaces with a sponge or cloth and wipe clean with a damp cloth.

Floor Cleaner: Mix ¼ cup of castile soap with a gallon of warmwater. Use a mop to clean your floors as usual.

Stainless Steel Cleaner: Mix 1/2 cup of olive oil with 1/2 cup of white vinegar. Add 10-20 drops of citrus essential oil. Spray onto stainless steel surfaces and wipe clean with a micro fiber cloth.

Shower and Tub Cleaner: Mix 1/2 cup of white vinegar with 1/2cup of Sal Suds. Apply the solution to the shower or tub using a spray bottle or a sponge. Let it sit for 3-5 minutes before scrubbing with a soft-bristled brush. Rinse thoroughly with water.

Basic Laundry Detergent: Mix 1 cup of washing soda, 1 cup of baking soda, 1/4 cup of Epsom salt, and 25 drops of essential oil in a large bowl. Store in a glass jar and use 1-2 tablespoons per load.

Vinegar Fabric Softener: Mix 1 cup of white vinegar with 20-30drops of essential oil in a spray bottle. Spray onto clothes before putting them in the dryer


Your Partner In Health,
Clarissa A. Kussin, ND, FMCHC, ERYT-1000

How to Talk About Food

Erica Nelson, MSPH, NBC-HWC

Here, at Carolina Total Wellness, we often recommend dietary adjustments to treat a wide variety of symptoms. Many of our patients come to us for guidance, asking ‘What is the healthiest diet?’ And the truth is, the ‘healthiest diet’ is unique to the person eating it.

One patient may get itchy and congested when they eat and need to reduce or eliminate foods that may increase or contain histamines like leftovers and peanuts. Another patient may have intestinal permeability and need to eliminate identified sensitives to gluten, oats and eggs. Yet another may be concerned about their family history of Alzheimer’s disease or cancer and need to make a variety of other adjustments.

Regardless of health status and dietary needs, most of us prefer sharing meals with our friends, family and coworkers over dining alone. Sometimes even a simple lunch can be a source of concern when a well-meaning aunt or friend asks about your ‘crazy diet.’

Over and over again, patients tell me that eating with their families is a barrier to successfully making the adjustments necessary to improve their health. Here are some strategies to enjoy eating the food that nourishes your body with the people that nourish your soul (and even some people that don’t):

Know your why. Get clear on why you are making the changes. And practice your responses ahead of time. When you know exactly what you are trying to accomplish with your food, it is easier to make good choices and much harder for someone else to convince you otherwise.

Have a short ‘elevator pitch’ prepared. Something like, ‘I wasn’t feeling my best recently and, after talking to my doctor, I am focused on eating foods that nourish my body and soul like (name a few key foods you’re enjoying eating.)’ And then mention a positive outcome like. ‘You wouldn’t believe how much better I am sleeping!’

Have at least one person fully in your corner. As part of your preparation for making these changes, make sure you talk to a trusted friend or partner that will be your support-person when the going gets tough. No matter how committed you are to health changes, there will be days when you don’t get enough rest or you have a bad day at the office. On these days, even strong-willed, prepared ‘you’ can have a tough time remembering your ‘why’ and the ‘Can’t you have just one bite?’ question may be coming from inside your own head. On these days, call this person and tell them that you are considering deviating from your plan.

Project confidence. Add a big smile to your ‘No thank you’ and you’re less likely to get pushback or hear ‘Can’t you have just one?’ Know your restaurant order before you go and say it confidently. ‘I’ll have the burger, no bun, no cheese, extra lettuce and the spinach salad on the side, please.’

“Girl (or boy,) stop apologizing.”  Rachel Hollis made this phrase famous with her book by the same name. She was right, though. There is no need to apologize for doing what is right for your health and/or sanity. Try replacing ‘I’m sorry’ with ‘Thank you.’ For example, instead of ‘I’m sorry to inconvenience you,’ try ‘Thank you for accommodating for my gluten/dairy/egg/sugar sensitivity.’

Boundaries. Some people have no trouble with the sentence ‘no.’ But for many, it is easier to please the people around you and silently suffer your own consequences later. This can be exhausting and lead to difficulty knowing what you wanted in the first place. Know where your line is and don’t let anyone tempt you to cross it. Remember that everything you say ‘yes’ to is a ‘no’ to something else.

It is okay to make inappropriate people uncomfortable. If, for example, someone makes a comment about your body composition or fertility, it is not only okay to make them uncomfortable, but also brave and good. Saying ‘That’s inappropriate’ could keep them from bestowing their judgement on another undeserving person.

The health coaches at Carolina Total Wellness are here to support you in your personalized health care journey.

Your Partner In Health,

Erica Nelson, MSPH, NBC-HWC

Hormesis: The Beneficial Type of Stress

Sara Yadlowsky, FMHC

What doesn’t kill you makes you stronger.  We’ve all heard the saying before.  Science has revealed it is surprisingly accurate when it comes to our health and longevity.

Hormesis is the idea that short, intermittent bursts of certain stressors can start a cascade of cellular processes that slow aging, improve overall health and make you more resilient, both physically and mentally.  It is a hot topic in longevity research right now.

We all know that chronic stress caused by relationship issues, financial problems and working too many hours is detrimental to our health.  However, hormetic stressors are controlled and acute, triggering healthy adaptive responses.

What does all this mean in real life?  Hormesis is the common thread found in some popular health and fitness trends such as HIIT (high intensity interval training), cold exposure, heat therapy and intermittent fasting.  Prolonged doses of these behaviors are not healthy or sustainable.   For example, if you spend too much time in a sauna you will become dehydrated.  But, in short bursts, the bodily stress caused by these practices are enough to bring about health benefits such as reducing inflammation, supporting elimination of toxins, repairing DNA, combatting oxidative stress, repairing cellular damage and reducing risk of cancer.

Here are three ways to strategically stress your body and reap the rewards:

  1. HIIT – Do a HIIT workout 1-3 times a week.  HIIT workouts are intermittent bursts of intense effort for 30 seconds, followed by 15 seconds of rest.  These workouts are usually short, around 15-20 minutes.  You can easily find these HIIT videos on YouTube.
  2. Hot or Cold Therapy – Infrared sauna is a great way to heat up and sweat out some toxins.  It also reduces inflammation and pain.  In contrast, ice baths, cold showers and the new cryotherapy chambers that are popping up everywhere will cool you down quicky.  Cold therapy is also known for reducing inflammation and pain.  Both types of therapies may help strengthen the immune system.
  3. Intermittent Fasting – Fasting triggers a cellular “clean up” response called autophagy.  Autophagy results in several health benefits such as lowered cholesterol, reduced blood pressure and reduced inflammation.  For many, a 16:8 intermittent fasting schedule (16 hours of fasting followed by an 8 hour feeding window) works well.  However, we recommend that you experiment with the timing to see what works best for you.

Be aware that adding stress (even the good type!) to our lives can backfire if done at the wrong time.  When life is already very stressful, it is best to wait until a better time when you are more relaxed to try out these new practices.

Your Partner In Health,

Sara Yadlowsky, FMHC